Timothy F Osborne Selected Research

Peroxisome Proliferator-Activated Receptors (PPAR)

5/2008

Peroxisome proliferator-activated receptor-gamma coactivator-1alpha activation of CYP7A1 during food restriction and diabetes is still inhibited by small heterodimer partner.

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Timothy F Osborne Research Topics

Disease

5	Inflammation (Inflammations) 04/2024 - 04/2011
5	Non-alcoholic Fatty Liver Disease 04/2024 - 10/2016
5	Neoplasms (Cancer) 12/2023 - 10/2008
3	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 05/2008
3	Insulin Resistance 01/2017 - 12/2012
2	Fibrosis (Cirrhosis) 04/2024 - 05/2018
2	Carcinogenesis 12/2023 - 01/2012
2	Obesity 01/2023 - 01/2021
2	Infections 10/2022 - 12/2003
2	Atherosclerosis 01/2021 - 04/2011
2	Alcoholic Fatty Liver 12/2019 - 05/2018
2	Hypoxia (Hypoxemia) 10/2011 - 05/2011
2	Hypercholesterolemia 11/2009 - 09/2003
1	Liver Cirrhosis (Hepatic Cirrhosis) 04/2024
1	Metaplasia 12/2023
1	Malnutrition (Nutritional Deficiencies) 10/2022
1	Virus Diseases (Viral Diseases) 10/2022
1	COVID-19 10/2022
1	Cytokine Release Syndrome 10/2022
1	RNA Virus Infections 10/2022
1	Abdominal Obesity 01/2022
1	Atherosclerotic Plaque (Atheroma) 01/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2020
1	Fatty Liver 12/2019
1	Hyperglycemia 11/2018
1	Liver Diseases (Liver Disease) 05/2018
1	Metabolic Diseases (Metabolic Disease) 05/2018
1	Body Weight (Weight, Body) 05/2015
1	Breast Neoplasms (Breast Cancer) 01/2012
1	Shock 05/2011
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 05/2011
1	Sudden Death 01/2008
1	Cardiac Arrhythmias (Arrythmia) 01/2008
1	Insulinoma 11/2005
1	Cysts 05/2004
1	Hypothyroidism 09/2003

Drug/Important Bio-Agent (IBA)

9	LipidsIBA 04/2024 - 01/2008
9	CholesterolIBA 04/2024 - 09/2003
6	Glucose (Dextrose)FDA LinkGeneric 06/2020 - 11/2005
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2008
3	Sterol Regulatory Element Binding Protein 1IBA 04/2024 - 05/2011
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 11/2009
3	Proteins (Proteins, Gene)FDA Link 01/2012 - 05/2004
2	Sterol Regulatory Element Binding ProteinsIBA 04/2024 - 01/2022
2	Histones (Histone)IBA 01/2021 - 05/2015
2	ChromatinIBA 06/2020 - 01/2011
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2020
2	Liver X ReceptorsIBA 01/2020 - 04/2011
2	SterolsIBA 12/2019 - 01/2012
2	Insulin (Novolin)FDA Link 01/2017 - 01/2017
2	Bile Acids and Salts (Bile Acids)IBA 05/2008 - 12/2003
1	Lipocalin-2IBA 04/2024
1	IronIBA 04/2024
1	Nonesterified Fatty Acids (NEFA)IBA 10/2022
1	Membrane Transport Proteins (Biological Pump)IBA 10/2022
1	CytokinesIBA 10/2022
1	Antiviral Agents (Antivirals)IBA 10/2022
1	Lipase (Acid Lipase)FDA Link 10/2022
1	Viral RNAIBA 10/2022
1	TensinsIBA 01/2022
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2021
1	Histone-Lysine N-MethyltransferaseIBA 01/2021
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2021
1	Dipyridamole (Persantine)FDA LinkGeneric 01/2021
1	Interferon Type IIBA 01/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2020
1	EnzymesIBA 12/2019
1	GSK5182IBA 12/2019
1	ElementsIBA 12/2019
1	Estrogens (Estrogen)FDA Link 12/2019
1	SugarsIBA 11/2018
1	AMP-Activated Protein KinasesIBA 05/2018
1	Messenger RNA (mRNA)IBA 05/2018
1	PF-6409577IBA 05/2018
1	lactisoleIBA 01/2017
1	SaccharinIBA 01/2017
1	Glucagon (Glukagon)FDA Link 01/2017
1	Triglycerides (Triacylglycerol)IBA 10/2016
1	Adrenergic Agents (Adrenergic Drugs)IBA 05/2015
1	Lysine (L-Lysine)FDA Link 05/2015
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 12/2012
1	Mevalonic Acid (Mevalonate)IBA 01/2012
1	DNA (Deoxyribonucleic Acid)IBA 10/2011
1	DioxygenasesIBA 10/2011
1	Oxygen (Dioxygen)IBA 10/2011
1	AndrogensIBA 11/2009
1	Phospholipids (Phosphatides)FDA LinkGeneric 10/2008
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 10/2008
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 05/2008
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2008
1	GTP-Binding Proteins (G-Protein)IBA 01/2008
1	LDL Receptors (LDL Receptor)IBA 09/2003
1	Nuclear Proteins (Protein, Nuclear)IBA 09/2003

Therapy/Procedure

2	Therapeutics 12/2023 - 11/2009
1	Chemoprevention 12/2023
1	Ligation 05/2011
1	Punctures 05/2011